HomeGeneric Rheumatrex

Generic Rheumatrex Methotrexate 2.5mg

Package	Price	Per Pill	Order
2.5mg × 30 pills	39.94	US $ 1.33
2.5mg × 60 pills	62.47	US $ 1.04
2.5mg × 90 pills	80.68	US $ 0.90
2.5mg × 120 pills	102.93	US $ 0.86

Rheumatrex(Methotrexate) is applied for:

Treating certain types of cancer, serious psoriasis, or rheumatoid arthritis in certain patients. It may be applied alone or with other preparations. It may also be applied for other conditions as determined by your doctor.

Rheumatrex(Methotrexate) is an antimetabolite. It works to treat cancer and psoriasis by blocking an enzyme necessary for cell growth. This helps to slow the growth of cancer cells and abnormal skin cells. Exactly how Methotrexate works to treat rheumatoid arthritis is unknown. It reduces symptoms of inflammation (eg, pain, swelling, stiffness) caused by rheumatoid arthritis.

More recently it has come into use as a treatment for some autoimmune diseases, including ankylosing spondylitis, Crohn's disease, psoriasis, psoriatic arthritis, and rheumatoid arthritis

Do NOT accept Rheumatrex if:

• you are allergic to any ingredient in Methotrexate
• you are treating psoriasis or rheumatoid arthritis and you are pregnant or breast-feeding
• you are treating psoriasis or rheumatoid arthritis and abuse alcohol or have liver disturbances, an immunodeficiency syndrome (eg, AIDS), bone marrow disturbances, or blood disturbances (eg, anemia, low white blood cell count, low platelet count)
• you have moderate or serious kidney disturbances
• you are accepting acitretin

Contact your doctor or health care provider right away if any of these apply to you.

Prior to using Rheumatrex(Methotrexate):

Some medical conditions may interact with Rheumatrex(Methotrexate). Inform your doctor or pharmacist in case you have any medical conditions, especially if any of the following apply to you:

• in case you are pregnant, planning to become pregnant, or are breastfeeding
• in case you are accepting any prescription or nonprescription preparation, herbal preparation, or dietary supplement
• in case you have allergies to preparations, foods, or other substances
• in case you have a history of lung disturbances, immune system disturbances, nervous system disturbances (eg, seizures), liver disturbances (eg, hepatitis), or blood disturbances (eg, anemia, low white blood cells, low blood platelets)
• in case you have an active infection, serious vomiting or diarrhea, or dehydration
• in case you have mouth sores, excess fluid in your stomach or around your lungs, stomach or intestinal ulcers, bowel inflammation (eg, ulcerative colitis), or a blockage of your stomach or bowel
• in case you have a folic acid deficiency, are in very poor health, or have a history of alcohol abuse
• in case you are receiving chemotherapy or radiation

Some PREPARATIONS MAY INTERACT with Rheumatrex(Methotrexate). Inform your health care provider in case you are accepting any other preparations, especially any of the following:

• Acitretin, azathioprine, etretinate, leflunomide, retinoids, or sulfasalazine because the danger of liver disturbances may be increased
• Chloramphenicol, corticosteroids (eg, prednisone), cyclosporine, dantrolene, hydantoins (eg, phenytoin), nonsteroidal anti-inflammatory preparations (NSAIDs) (eg, ibuprofen, celecoxib), penicillin antibiotics, phenylbutazone, pristinamycin, probenecid, quinolone antibiotics (eg, ciprofloxacin), salicylates (eg, aspirin), sulfonamides (eg, sulfamethoxazole), tetracycline, or trimethoprim because they may raise the danger of Methotrexate's by-effects
• Folic acid or leucovorin because they may reduce Methotrexate's effectiveness
• Digoxin because its effectiveness may be reduced by Methotrexate
• Anticoagulants (eg, warfarin), cyclosporine, or theophylline because the danger of their by-effects may be increased by Methotrexate

This may not be a complete list of all interactions that may arise. Ask your health care provider if Methotrexate may interact with other preparations that you accept. Check with your health care provider prior to you start, stop, or change the dose of any preparation.

How to accept Methotrexate:

Accept Methotrexate as directed by your doctor. Check the label on the preparation for exact dosing recommendations.

• Accept Methotrexate by mouth with or without food. However, you should accept it the same way each time in relation to food.
• Drinking extra fluids while you are accepting Methotrexate is recommended. Check with your doctor for recommendations.
• Be convinced you understand exactly how much of Methotrexate to accept and how often you should accept it. Ask your doctor or pharmacist in case you have any questions.
• It may take several weeks for your symptoms to improve. Do not stop accepting Methotrexate without checking with your doctor.
• Methotrexate works best if each dose is taken at the scheduled time.
• Continue to accept Methotrexate even in case you feel well. Do not miss any doses.
• In case you miss a dose of Methotrexate, contact your doctor right away. Do not accept 2 doses at once.

Ask your health care provider any questions you may have about how to accept Rheumatrex(Methotrexate).

Important safety information:

• Methotrexate may cause drowsiness, dizziness, or blurred eyesight. These effects may be worse in case you accept it with alcohol or certain preparations. Accept Methotrexate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Check with your doctor prior to you drink alcohol while you are accepting Methotrexate.
• Nausea, vomiting, and loss of appetite are common with Methotrexate. Ask your doctor or pharmacist for ways to reduce these effects if they arise.
• If vomiting or diarrhea arises, you must take care not to become dehydrated. Contact your doctor for recommendations.
• Methotrexate may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Methotrexate. Accept a sunscreen or wear protective clothing in case you must be outside for more than a short time.
• Methotrexate may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Inform your doctor in case you have unusual bruising or bleeding. Inform your doctor in case you have dark, tarry, or bloody stools.
• Methotrexate may reduced the ability of your body to fight infection. Avoid contact with people who have colds or infections. Inform your doctor in case you notice symptoms of infection like fever, sore throat, rash, or chills.
• Do not receive a live vaccine (eg, measles, mumps) while you are accepting Methotrexate. Talk with your doctor prior to you accept any vaccine.
• Men who accept Methotrexate should always use a condom when having sex with a woman who may become pregnant. Do this for as long as you accept Methotrexate and for 3 months after you stop accepting it.
• Do NOT accept more than the recommended dose or accept for longer than prescribed without checking with your doctor.
• Lab tests, including albumin levels, complete blood counts, and liver, lung, and kidney function, may be performed while you accept Methotrexate. These tests may be applied to monitor your condition or check for by-effects. Be convinced to keep all doctor and lab appointments.
• Accept Methotrexate with caution in the ELDERLY; they may be more sensitive to its effects.
• Methotrexate should be applied with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Methotrexate may cause birth defects and fetal and newborn death in case you accept it while you are pregnant. Do not become pregnant while you are using it. Use an effective form of birth control while you accept Methotrexate and for at least 1 ovulatory cycle after you stop accepting it. In case you think you may be pregnant, contact your doctor right away. Methotrexate is found in breast milk. Do not breast-feed while accepting Methotrexate.

Possible by-effects of Methotrexate:

All preparations may cause by-effects, but many people have no, or minor, by-effects. Check with your doctor if any of these most COMMON by-effects persist or become bothersome:

Dizziness; headache; loss of appetite; mild hair loss; nausea; stomach pain or upset; tiredness; vomiting.

Seek medical attention right away if any of these SERIOUS by-effects arise:

Serious allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in the urine; calf or leg pain or swelling; change in the amount of urine; pain in the chest; coma; confusion; coughing up blood; dark urine; diarrhea; difficult or painful urination; dry cough; fever, chills, or sore throat; menstrual changes; mental or mood changes; mouth sores; one-sided weakness; red, swollen, peeling, or blistered skin; seizures; serious or persistent nausea or vomiting; shortness of breath; speech changes; unusual bleeding or bruising; unusual pain and discoloration of the skin; unusual weariness or weakness; eyesight changes or loss of sight; yellowing of skin or eyes.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.